Medical Resarch Library
This page contains a number of medical research studies pertaining to metal debris wear of metal-on-metal hip implants, cobalt & chromium toxicity, metal hypersensitivity, and other issues surrounding the DePuy ASR hip implant recall.
If you have questions or would like to discuss your case with a medical device recall lawyer, fill out the contact form on this page, or call 888-290-4472 for a free & confidential case evaluation.
- FDA Executive Summary Memorandum for Metal-on-Metal Hip Implant Systems Prepared for the June 27-28, 2012 Meeting of the Orthopaedic and Rehabilitation Devices Advisory Panel
- Appendix I: Summary of Medical Device Adverse Event Reports (for FDA Executive Meeting June 27-28, 2012)
- Medical Device Alert: All metal-on-metal (MOM) hip replacements, February 28, 2012
- Cobalt Toxicity: An emerging clinical problem in patients with metal-on-metal hip prostheses? Medical Journal of Australia, May 26, 2011
- Arthroprosthetic Cobaltism: Neurological and Cardiac Manifestations in Two Patients with Metal-on-Metal Arthroplasty: A Case Report Journal of Bone & Joint Surgery, October 29, 2010
- Metal Release in Patients Who Have Had a Primary Total HIp Arthroplasty, The Journal of Bone & Joint Surgery, September 27, 2010
- Metal-on-Metal Bearings in Primary Total Hip Arthroplasty: Minimum 2-year Follow Up, Joint Implant Surgeons, Inc., March 9-13, 2010
- Metal Hypersensitivity Testing in Total Joint Arthroplasty Patients, Joint Implant Surgeons, Inc. March 9-13, 2010
Metal-on-Metal Bearing Surfaces Perspectives on Modern Orthopaedics, February 2009 - Loosening and Osteolysis Associated with Metal-on-Metal Bearings: a Local Effect of MetalHypersensitivity? The Journal of Bone & Joint Surgery, September 4, 2010
- Modern Metal-on-Metal Hip Resurfacing, Journal of the American Academy of Orthopaedic Surgeons, May 2010
- The Validity of Serum Levels as a Surrogate Measure of Systemic Exposure to Metal Ions in Hip Replacement, Journal of Bone & Joint Surgery, 2007
- Metallosis due to impingement between the socket and the femoral head in a total hip prosthesis. A case report. 2002, Journal of Bone & Joint Surgery
- Cobalt-Chromium-Molybdenum Alloy Causes Metal Accumulation and Metallothionein Up-Regulation in Rat Liver and Kidney, Department of Neurobiology, Institute of Anatomy, University of Aarhus, Aarhus, Denmark
- Metal Ion Toxicity References 1996 – 2002
- Carcinogenicity of Hexavalent Chromium, Wise Laboratory of Environmental & Genetic Toxicology, Maine Center for Toxicology, October 2008
- Complications Associated with Hip Resurfacing Arthroplasty, Orthopedic Clinics of North America, 2005
- DePuy ASR Hip Prosthesis Index to Research Materials
- Early Failure of Metal-on-Metal Bearings in Hip Resurfacing and Large-Diameter Total Hip Replacement: A Consequence of Excess Wear, The Journal of Bone & Joint Surgery, January 2010
- The Effects of Component Size and Orientation on the Concentrations of Metal Ions After Resurfacing Arthroplasty of the Hip, The Journal of Bone & Joint Surgery, September 2008
- Metal Ion Measurement as a Diagnostic Tool to Identify Problems with Metal-on-Metal Hip Resurfacing, The Journal of Bone & Joint Surgery, September 4, 2010
- Loosening and Osteolysis Associated with Metal-on-Metal Bearings: A Local Effect of Metal Hypersensitivity? The Journal of Bone & Joint Surgery, September 4, 2010
- Complications Associated with Hip Resurfacing Arthroplasty, Orthopedic Clinics of North America, 2005
- Articular Surface Replacement of the Hip: A Prospective Single-Surgeon Series, The Journal of Bone & Joint Surgery, 2010
- Elevated Levels of Cobalt and Chromium Found in Offspring of Moms with Metal-on-Metal Hip Implants Rush University Medical Center, March 9, 2010
- World Health Organization International Agency for Research on Cancer (IARC) Monographs on the Evaluation of Carcingenic Risks to Humans Volume 86: Cobalt in Hard Metals and Cobalt Sulfate, Gallium Arsenide, Indium Phosphide and Vanadium Pentoxide, 2006
- Cellular and Molecular Pathways Linking Inflammation and Cancer, University of Piemonte Orientale A. Avogadro, Novara, Italy, July 17, 2009
- Four-year study of cobalt and chromium blood levels in patients managed with two different metal-on-metal total hip replacements, March 2003, Journal of Orthopaedic Research
- Metallosis due to impingement between the socket and the femoral head in a total hip prosthesis. A case report. 2002, Journal of Bone Joint Surgery